Anti-SETD7

Anti-SETD7
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG58984.50 50 µl - -

6 - 14 Werktage*

551,00 €
 
Protein function: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone... mehr
Produktinformationen "Anti-SETD7"
Protein function: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys- 189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. [The UniProt Consortium]
Schlagworte: Anti-SETD7, Anti-SET7/9, Anti-SET7/9, Anti-KIAA1717, Anti-H3-K4-HMTase SETD7, Anti-H3-K4-HMTase SETD7, Anti-Lysine N-methyltransferase 7, Anti-Lysine N-methyltransferase 7, Anti-SET domain-containing protein 7, Anti-SET domain-containing protein 7, Anti-H
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG58984

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: Recombinant fusion protein corresponding to aa. 1-366 of Human SETD7 (NP_085151.1)
MW: 41 kD
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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