Anti-SAFB1 (2E8) [2E8-E2-G6] Monoclonal Antibody

SAFB1 (2E8) Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (PubMed:9671816). Functions as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription (PubMed:12660241). Thereby acts as a negative regulator of cell proliferation (PubMed:12660241). When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity) [The Uniprot Consortium]