Anti-RNF130

ring finger protein 130(RNF130) Homo sapiens The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], Protein function: May have a role during the programmed cell death of hematopoietic cells. Acts as an E3 ubiquitin-protein ligase. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000. Cellular localization: Membrane , Single-pass type I membrane protein . Cytoplasm .