Anti-Rho, clone 4D2

Anti-Rho Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Rhodopsin from all mammalian species (human, mice, rat, bovine, pig etc.), most fish, birds, amphibians (frogs, Xenopus), anchovies based on 100% homology with the immunizing sequence. Not Drosophila or other invertebrates. Cross-reactivity with Rhodopsin from other sources has not been determined. Signaling and GTPase research. Protein function: Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal. [The UniProt Consortium]