Anti-REG1A

REG1A (regenerating islet-derived 1 alpha), also known as PTP, PSP, is a member of the Reg family of secreted proteins with a C-type lectin domain. REG1A is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis.Due to variable glycosylation, pancreatic REG1A exists as multiple species of 16-18kD. REG1A promotes the maintenance and growth of pancreatic islet beta-cells and intestinal villi. It is upregulated in pancreatitis and some carcinomas. REG1A is an antigenic target in autoimmune diabetes. Applications: Immunohistochemistry: 1:200-1:1000., Immunofluorescence: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.