Anti-Recombinant S100A1, clone A415

S100A1 is a member of the S100 protein family, each of which contains two EF-hand calcium-binding motifs. These proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. At least 13 S100 genes are clustered on chromosome 1q21. S100A1 may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.