Anti-RANKL (human)

Recognizes human RANKL. Detects a band of about 35kDa band by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. RANKL is an osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. Important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. Plays an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.