Anti-Rad21 Recombinant Monoclonal

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A700-052-T 20 µl (2 blots) -

2 - 8 Werktage*

172,00 €
A700-052 100 µl (10 blots) -

2 - 8 Werktage*

416,00 €
 
Protein function: Cleavable component of the cohesin complex, involved in chromosome cohesion... mehr
Produktinformationen "Anti-Rad21 Recombinant Monoclonal"
Protein function: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway. [The UniProt Consortium]
Schlagworte: Anti-HR21, Anti-hHR21, Anti-NXP-1, Anti-RAD21, Anti-SCC1 homolog, Anti-Nuclear matrix protein 1, Anti-Double-strand-break repair protein rad21 homolog
Hersteller: Bethyl Laboratories
Hersteller-Nr: A700-052

Eigenschaften

Anwendung: WB, FC
Antikörper-Typ: Monoclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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