Anti-PSMD14

Anti-PSMD14
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A303-857A-T 10 µl (10 µg) -

2 - 8 Werktage*

164,00 €
A303-857A 100 µl (100 µg) -

2 - 8 Werktage*

588,00 €
 
Protein function: Metalloprotease component of the 26S proteasome that specifically cleaves... mehr
Produktinformationen "Anti-PSMD14"
Protein function: Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. Plays a role in response to double-strand breaks (DSBs): acts as a regulator of non-homologous end joining (NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading. [The UniProt Consortium]
Schlagworte: Anti-POH1, Anti-PSMD14, EC=3.4.19.-, Anti-26S proteasome regulatory subunit RPN11, Anti-26S proteasome-associated PAD1 homolog 1, Anti-26S proteasome non-ATPase regulatory subunit 14
Hersteller: Bethyl Laboratories
Hersteller-Nr: A303-857A

Eigenschaften

Anwendung: WB, IP
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse (Erwartet: rat, zebrafish, X. laevis, X. tropicalis, chicken, turkey, bovine, horse, guinea pig_10141, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, west indian ocean coelacanth, channel catfish, atlantic salmon, sablefish)
Immunogen: synthetic peptide. The epitope recognized by A303-857A-T maps to a region between residue 260 and 310 of human Proteasome (Prosome, Macropain) 26S Subunit, non-ATPase, 14 using the numbering given in entry NP_005796.1 (GeneID 10213).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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