Anti-PSCA (PRO232, Prostate Stem Cell Antigen)

PSCA (prostate stem cell antigen) is a glycosylphosphatidylinositol (GPI)­anchored cell surface protein of the Thy­1/Ly­6 family. PSCA is expressed in differentiating cells and epithelial cells of the prostate, bladder, kidney, skin, esophagus, stomach and placenta. It may be up­ or down­regulated in cancer and may promote or suppress the tumor, depending on location. Mature human PSCA (aa21­95) shares ~65% amino acid sequence identity with mouse and rat PSCA. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 8­25ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.