Anti-PLPPR5

The protein encoded by this gene is a type 2 member of the phosphatidic acid phosphatase (PAP) family. All type 2 members of this protein family contain 6 transmembrane regions, and a consensus N-glycosylation site. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Protein function: Induces filopodia formation and promotes neurite growth in a CDC42-independent manner, impedes neurite growth inhibitory-mediated axonal retraction. [The UniProt Consortium]