Anti-Plasmodium falciparum, HRP2 (Malaria)

Plasmodium falciparum histidine rich protein-2 is a 33kD member of the histidine rich protein family found in the malaria parasite. Histidine rich protein-2 is secreted by Plasmodium falciparum into the host erythrocyte cytosol and is expressed on the cell membrane or associated with the cytoskeleton of infected erythrocytes. Histidine rich protein-2 is thought to polymerise free haem to form haemozoin. It is also thought to play a role in the polymerisation of ferriprotoporphyrin IX, a by-product of haemoglobin degradation. Applications: Suitable for use in ELISA and Lateral Flow. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Matched Pair: Capture: P4256-67D , Detection: P4256-71C, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.