Anti-PHOX2B

Anti-PHOX2B Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. PHOX2B antibody is predicted to not cross-react with other paired homeobox family members. Protein function: Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum- response element. [The UniProt Consortium]