Anti-PHC1 (8G5) [8G5-1E6-3G7] Monoclonal Antibody

PHC1 (8G5) Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression [The Uniprot Consortium]