Anti-Pax-2, clone YN01275r

Pax-2 is a member of Pax transcription factor family. Pax-8 and Pax-2 participate in the formation of renal organs. In non-tumor tissues, Pax-2 is expressed in glomerular wall epithelial cells, renal collecting duct cells, atrophic renal tubular cells, ovarian surface epithelial cells, fallopian tubes, endometrium, endometrium. In primary tumors, Pax-2 is mainly expressed in renal cell carcinoma and nephrogenic tumor. Recent studies have shown that Pax-2 can be used as an effective immunohistochemical marker for the judging of renal epithelial cell tumors and some gynecological tumors. Protein function: Transcription factor that may have a role in kidney cell differentiation (PubMed:24676634). Has a critical role in the development of the urogenital tract, the eyes, and the CNS. [The UniProt Consortium]