Anti-PACS1

Polyclonal Antibody against Human PACS1, Gene description: phosphofurin acidic cluster sorting protein 1, Alternative Gene Names: FLJ10209, KIAA1175, Validated applications: ICC, Uniprot ID: Q6VY07, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Coat protein that is involved in the localization of trans- Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster- containing cytoplasmic domain of these molecules with the adapter- protein complex-1 (AP-1) of endosomal clathrin-coated membrane pits. Involved in HIV-1 nef-mediated removal of MHC-I from the cell surface to the TGN. [The UniProt Consortium] Mouse gene identity: 88% Rat gene identity: 88%