Anti-p16

This product was prepared from monospecific antiserum by delipidation and defibrination.  Antiserum will specifically react with a p16 protein from human  tissue.  Cross reactivity may occur with p15 when immunoprecipitating in vitro translated product but not in immunoblots.  Potentially cross reacts with p15.5. Protein function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. [The UniProt Consortium]