Anti-p150 CAF1 [R06-8D4] Monoclonal Antibody

p150 CAF1 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci [The Uniprot Consortium]