Anti-NOG2

function:GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.,similarity:Belongs to the MMR1/HSR1 GTP-binding protein family. NOG2 subfamily.,tissue specificity:Ubiquitously expressed at relatively low levels in all human tissues tested, with the highest level of expression in the testes., Protein function: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (PubMed:32669547). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Nucleus, nucleolus .