Anti-NIPA2

This gene encodes a possible magnesium transporter. This gene is located adjacent to the imprinted domain in the Prader-Willi syndrome deletion region of chromosome 15. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 7 and 21.[provided by RefSeq, May 2010], Protein function: Acts as a selective Mg(2+) transporter. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Cell membrane , Multi-pass membrane protein . Early endosome . Recruited to the cell membrane in response to low extracellular magnesium. .