Anti-Myoglobin

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Human Myoglobin (MG) has 152 residues. Two MG variants were found. The Myoglobin locus mapped to 22q11-22q13. The gene is about 10.5 kb long and contains two introns as in the case with hemoglobin genes. Myoglobin/MG may serve a variety of functions in muscular oxygen supply, such as O2 storage, facilitated O2 diffusion, and Myoglobin-mediated oxidative phosphorylation. Protein function: Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand (PubMed:10468637, PubMed:11304494). Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity (PubMed:15132981). [The UniProt Consortium]