Anti-MVB12A

MVB12A (Multivesicular Body Subunit 12A) is a Protein Coding gene. Diseases associated with MVB12A include Hemolytic Uremic Syndrome, Atypical 1 and Potocki-Shaffer Syndrome. Among its related pathways are Endocytosis. Gene Ontology (GO) annotations related to this gene include lipid binding and ubiquitin binding. Protein function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor. [The UniProt Consortium]