Anti-MD-2

Anti-MD-2 Antibody is purified by ion exchange chromatography. Cross reactivity with MD-2 from other sources has not been determined. Protein function: Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS. [The UniProt Consortium]