Anti-MCAK [R06-2D7] Monoclonal Antibody -Knockout Validated

[KD] MCAK Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PubMed:21820309). Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (PubMed:19060894). Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (PubMed:23891108) [The Uniprot Consortium]