Anti-MAP3K20

Anti-MAP3K20
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-RQ4056 100 µg - -

3 - 10 Werktage*

628,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Sterile alpha motif and leucine zipper... mehr
Produktinformationen "Anti-MAP3K20"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Sterile alpha motif and leucine zipper containing kinase AZK, also known as ZAK, is a human gene. This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Protein function: Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2 (PubMed:10924358, PubMed:11836244, PubMed:15342622, PubMed:21224381). Involved in limb development (PubMed:26755636). [The UniProt Consortium]
Schlagworte: Anti-MRK, Anti-MLTK, Anti-HCCS4, Anti-HCCS-4, EC=2.7.11.25, Anti-MLK-related kinase, Anti-Mixed lineage kinase-related kinase, Anti-Human cervical cancer suppressor gene 4 protein, Anti-MLK-like mitogen-activated protein triple kinase, MAP3K20 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: RQ4056

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Mouse
Immunogen: A recombinant human partial protein corresponding to amino acids F276-E511 was used as the immunogen for the MAP3K20 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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