Anti-LTK

Anti-LTK
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R31096 100 µg - -

3 - 10 Werktage*

755,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Leukocyte tyrosine kinase, also known as... mehr
Produktinformationen "Anti-LTK"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Leukocyte tyrosine kinase, also known as TYK1, is an enzyme that in humans is encoded by the LTK gene. The protein encoded by this gene is a member of the ALK/LTK receptor family of receptor tyrosine kinases (RTKs) whose ligand is unknown. Toyoshima et al.(1993) cloned a set of cDNAs representing differently spliced human LTK mRNAs. Liao et al.(1996) found that the mouse Ltk gene is closely linked to the Tyro3 gene which maps to mouse chromosome 2. Thus, the gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions. Protein function: Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport. [The UniProt Consortium]
Schlagworte: Anti-LTK, Anti-TYK1, EC=2.7.10.1, Anti-Protein tyrosine kinase 1, Anti-Leukocyte tyrosine kinase receptor, LTK Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: R31096

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: An amino acid sequence from the C-terminus of human Leukocyte tyrosine kinase (RGLQPQNLWNPTYRS) was used as the immunogen for this LTK antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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