Protein function: RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5'cap in an MTOR-dependent manner and associates with mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5'TOP, thereby regulating cell growth and proliferation. Positively regulates the replication of dengue virus (DENV) (PubMed:26735137). [The UniProt Consortium]
Anti-LARP1, Anti-KIAA0731, Anti-La-related protein 1, Anti-La ribonucleoprotein domain family member 1
synthetic peptide. The epitope recognized by A302-088A-T maps to a region between residue 575 and 625 of human La ribonucleoprotein domain family, member 1 using the numbering given in entry NP_291029.2 (GeneID 23367).