Protein function: Binds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single- stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'- UTR, possibly by recruiting degradation machinery to ARE- containing mRNAs. [The UniProt Consortium]
Anti-p75, Anti-KSRP, Anti-FUBP2, Anti-KHSRP, Anti-FUSE-binding protein 2, Anti-KH type-splicing regulatory protein, Anti-Far upstream element-binding protein 2
Human, Mouse (Erwartet: Bovine, Dog, Horse, Guinea Pig_10141, Pig, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, European Domestic Ferret, Small-eared Galago, Little Brown Bat)
synthetic peptide. The epitope recognized by A302-021A-T maps to a region between residue 100 and 150 of human KH-type splicing regulatory protein using the numbering given in entry Q92945.3 (GeneID 8570).