Anti-Ki-67 (IHC)

Anti-Ki-67 (IHC)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
IHC-00395-T 10 µl (5+ slides) -

3 - 9 Werktage*

131,00 €
IHC-00395 100 µl (50+ slides) -

3 - 9 Werktage*

493,00 €
 
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm... mehr
Produktinformationen "Anti-Ki-67 (IHC)"
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). [The UniProt Consortium]
Schlagworte: Anti-Antigen Ki67, Anti-Antigen KI-67, Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by monoclonal antibody Ki-67
Hersteller: Bethyl Laboratories
Hersteller-Nr: IHC-00395

Eigenschaften

Anwendung: IHC, IHC-IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: synthetic peptide. The epitope recognized by IHC-00395 maps to a region between residues 1800 and 1850 of human Ki-67 using the numbering given in entry NP_002408.2 (GeneID 4288).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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