Anti-IPO11

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-52788.20 20 µl -

7 - 16 Werktage*

71,00 €
E-AB-52788.60 60 µl -

7 - 16 Werktage*

143,00 €
E-AB-52788.120 120 µl -

7 - 16 Werktage*

238,00 €
E-AB-52788.200 200 µl -

7 - 16 Werktage*

396,00 €
 
Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport... mehr
Produktinformationen "Anti-IPO11"
Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1, 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]). Protein function: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of UBE2E3, and of RPL12. [The UniProt Consortium]
Schlagworte: Anti-Imp11, Anti-IPO11, Anti-RANBP11, Anti-RanBP11, Anti-Importin-11, Anti-Ran-binding protein 11, IPO11 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-52788

Eigenschaften

Anwendung: WB, IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
Immunogen: Fusion protein of human IPO11

Datenbank Information

UniProt ID : Q9UI26 | Passende Produkte
Gene ID : GeneID 51194 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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