Anti-Hydroxyl-Histone H2A (Tyr39) [R04-5I3] Monoclonal Antibody

Hydroxyl-Histone H2A (Tyr39) Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling [The Uniprot Consortium]