Anti-HOXA10

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Homeobox protein A10 is a protein that in humans is encoded by the HOXA10 gene. It is expressed in the adult human endometrium, and the expression dramatically increased during the midsecretory phase of the menstrual cycle, corresponding to the time of implantation and increase in circulating progesterone. HOXA10 may have an important function in regulating endometrial development during the menstrual cycle and in establishing conditions necessary for implantation in the human. HOXA10 is also a master regulator of postnatal hematopoietic development whose tight regulation is required for normal development of erythroid and megakaryocytic lineages. Protein function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to the DNA sequence 5'-AA[AT]TTTTATTAC-3'. [The UniProt Consortium]