Anti-HINT1

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-16478.20 20 µl -

7 - 16 Werktage*

71,00 €
E-AB-16478.60 60 µl -

7 - 16 Werktage*

143,00 €
E-AB-16478.120 120 µl -

7 - 16 Werktage*

238,00 €
E-AB-16478.200 200 µl -

7 - 16 Werktage*

396,00 €
 
The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine... mehr
Produktinformationen "Anti-HINT1"
The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene. Protein function: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His- AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O- phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin- protein ligase complex. [The UniProt Consortium]
Schlagworte: Anti-HINT, Anti-HINT1, Anti-PKCI-1, EC=3.-.-.-, Anti-Protein kinase C inhibitor 1, Anti-Adenosine 5'-monophosphoramidase, Anti-Protein kinase C-interacting protein 1, Anti-Histidine triad nucleotide-binding protein 1, HINT1 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-16478

Eigenschaften

Anwendung: WB, IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: Synthetic peptide of human HINT1
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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