Anti-HIF-1 beta

Anti-HIF-1 beta
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R31550 100 µg - -

3 - 10 Werktage*

755,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. HIF-1 beta is also known as ARNT or HIF1B.... mehr
Produktinformationen "Anti-HIF-1 beta"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. HIF-1 beta is also known as ARNT or HIF1B. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. It is mapped to 1q21.3. The protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. HIF-1 beta is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. It is a structural component of the XRE-binding form of the Ah receptor. It also functions in concert with RelB in a CD30-induced negative feedback mechanism. Protein function: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia. [The UniProt Consortium]
Schlagworte: Anti-ARNT, Anti-BHLHE2, Anti-bHLHe2, Anti-HIF1-beta, Anti-HIF-1-beta, Anti-ARNT protein, Anti-Hypoxia-inducible factor 1-beta, Anti-Dioxin receptor, nuclear translocator, Anti-Class E basic helix-loop-helix protein 2, HIF-1 beta Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: R31550

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Human partial recombinant protein (AA 416-789) was used as the immunogen for this HIF-1 beta antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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