Anti-Grik1

Anti-Grik1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Grik1 from other sources has not been determined. Protein function: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. [The UniProt Consortium]