Anti-GLUR3

Anti-GLUR3
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R31373 100 µg - -

3 - 10 Werktage*

755,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate receptor 3 is a protein that in... mehr
Produktinformationen "Anti-GLUR3"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. In addition, GLUR3 has been shown to interact with GRIP1 and PICK1. Protein function: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. [The UniProt Consortium]
Schlagworte: Anti-GLUR3, Anti-GRIA3, Anti-GluA3, Anti-GluR-3, Anti-GluR-C, Anti-GluR-K3, Anti-Glutamate receptor 3, Anti-AMPA-selective glutamate receptor 3, Anti-Glutamate receptor ionotropic, AMPA 3, GLUR3 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: R31373

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: An amino acid sequence from the middle region of human Glutamate receptor 3 (RKAGYWNEYERFVPFSDQQ) was used as the immunogen for this GLUR3 antibody (100% homologous in human, mouse and rat).
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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