Anti-GFER

Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide. Identity-Mouse (%): 68%. Homologies: Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 63%, Pig - 87%, Cynomolgus monkey - 74%. IHC Verification: -. WB Verification: succeed. IP Verification: -. IF Verification: -. FC Verification: -. IP-MS Verification: -. Cross reactivity: Not tested. Sandwich ELISA Verification: -. Antigen ID: ABS-PP-1244. Core Sequence: GARSEMMDDL ATDARGRGAG RRDAAASAST PAQAPTSDSP VAEDASRRRP CRACVDFKTW MRTQQKRDTK. Recombinant Antibody: Protein Function: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen , May act as an autocrine hepatotrophic growth factor promoting liver regeneration [The Uniprot Consortium]