Anti-Gelsolin, clone GEL-42

Anti-Gelsolin antibody was purified from mouse ascites by protein A chromatography.  This product reacts with human and rabbit. Cross reactivity with Gelsolin from other sources has not been determined. Protein function: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. [The UniProt Consortium]