Anti-GARP (human), clone ANC8C9, FITC conjugated

Antibody ANC8C9 binds to recombinant GARP in EIA and to cell surface GARP expressed on a subset of FOXP3 positive cells. GARP (LRRC32) is a ~80kD transmembrane glycoprotein expressed on the cell surface of megakaryocytes, platelets and a subset of activated regulatory T (Treg) cells. It is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells.