Anti-Frizzled 2

Anti-Frizzled 2
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R35814-100UG 100 µg - -

3 - 10 Werktage*

549,00 €
 
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... mehr
Produktinformationen "Anti-Frizzled 2"
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: FZD2 Protein function: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. [The UniProt Consortium]
Schlagworte: Anti-FZD2, Anti-hFz2, Anti-FzE2, Anti-Fz-2, Anti-Frizzled-2, Frizzled 2 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: R35814

Eigenschaften

Anwendung: IHC, ELISA (peptide)
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Goat
Reaktivität: Human
Immunogen: Amino acids RYATLEHPFHCPR were used as the immunogen for this Frizzled 2 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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