Anti-FCGR2B

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-15026.20 20 µl -

7 - 16 Werktage*

71,00 €
E-AB-15026.60 60 µl -

7 - 16 Werktage*

143,00 €
E-AB-15026.120 120 µl -

7 - 16 Werktage*

238,00 €
E-AB-15026.200 200 µl -

7 - 16 Werktage*

396,00 €
 
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin... mehr
Produktinformationen "Anti-FCGR2B"
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. Protein function: Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. [The UniProt Consortium]
Schlagworte: Anti-CD32, Anti-CDw32, Anti-FCGR2B, Anti-FcRII-b, Anti-Fc-gamma-RIIb, Anti-Fc-gamma RII-b, Anti-IgG Fc receptor II-b, Anti-Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-15026

Eigenschaften

Anwendung: WB, IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant protein of human FCGR2B
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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