Anti-ERp57

Anti-ERp57
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R30764 100 µg - -

3 - 10 Werktage*

755,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. PDIA3 (Protein disulfide isomerase family... mehr
Produktinformationen "Anti-ERp57"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. PDIA3 (Protein disulfide isomerase family A, member 3), also called GRP58, ERp57 or ER60, is an isomerase enzyme, mapped on 15q15.3. The PDIA3 protein has protein disulfide isomerase activity. It is also part of the major histocompatibility complex(MHC) class I peptide-loading complex, which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface. Koivunen et al. showed that PDIA3/ERp57 could not substitute for the beta subunit of PDI. When coexpressed with alpha prolyl 4-hydroxylase, it did not form prolyl 4-hydroxylase tetramers, nor did it have prolyl 4-hydroxylase activity. Hirano et al. expressed human ERp57 and found that the protein had a thiol-dependent reductase activity. They showed that the expression level increased after oncogenic transformation of normal rat kidney cells and NIH 3T3 cells.
Schlagworte: Anti-p58, Anti-PDIA3, Anti-ERP57, Anti-ERp57, Anti-ERp60, EC=5.3.4.1, Anti-ER protein 57, Anti-ER protein 60, Anti-58 kDa microsomal protein, Anti-Disulfide isomerase ER-60, Anti-Protein disulfide-isomerase A3, Anti-58 kDa glucose-regulated protein, ERp57
Hersteller: NSJ Bioreagents
Hersteller-Nr: R30764

Eigenschaften

Anwendung: WB, IHC (paraffin)
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: Amino acids 172-188 (LKAASNLRDNYRFAHTN) were used as the immunogen for this ERp57 antibody (100% homologous in human, mouse and rat).
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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