Anti-EIF2S2

Polyclonal Antibody against Human EIF2S2, Gene description: eukaryotic translation initiation factor 2 subunit beta, Alternative Gene Names: EIF2, EIF2beta, PPP1R67, Validated applications: IHC, Uniprot ID: P20042, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. [The UniProt Consortium] Mouse gene identity: 100% Rat gene identity: 100%