Protein function: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon- dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins. [The UniProt Consortium]
Human (Erwartet: Gorilla, Chimpanzee, White-tufted-ear Marmoset, Northern White-cheeked Gibbon)
synthetic peptide. The epitope recognized by A301-948A-T maps to a region between residue 450 and 500 of human eukaryotic translation initiation factor 2A, 65kDa using the numbering given in entry NP_114414.2 (GeneID 83939).