Anti-DYH8

Protein function: Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity, the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility, implicated in sperm flagellar assembly. [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Cytoplasm, cytoskeleton, flagellum axoneme . Cytoplasm . Detected in sperm tail, with almost exclusive localization to the principal piece. Also detected in the cytoplasm of primary spermatocytes. .