Anti-Drosha (IHC)

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
IHC-00389-T 10 µl (5+ slides) -

3 - 9 Werktage*

131,00 €
IHC-00389 100 µl (50+ slides) -

3 - 9 Werktage*

493,00 €
 
Protein function: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is... mehr
Produktinformationen "Anti-Drosha (IHC)"
Protein function: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA- ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double- strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. [The UniProt Consortium]
Schlagworte: Anti-RN3, Anti-p241, Anti-DROSHA, Anti-RNase III, Anti-Ribonuclease 3, Anti-Protein Drosha, Anti-Ribonuclease III
Hersteller: Bethyl Laboratories
Hersteller-Nr: IHC-00389

Eigenschaften

Anwendung: IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00389 maps to a region between residue 1324 and 1374 of human double-stranded RNA-specific endoribonuclease using the numbering given in entry NP_037367.3 (GeneID 29102).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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