Anti-Cyclin A2 (S- & G2-phase Cyclin), clone E67

Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cytoplasm, Nucleus. Positive Control: K-562 and HeLa cells. Human tonsil or lymph node. Chromosome Location: 4q27. Protein Function: Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle [The Uniprot Consortium]