Anti-Cyclin A1 (Cyclin-A1, CCNA1)

Anti-Cyclin A1 (Cyclin-A1, CCNA1)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
C8452-71B.100 100 µg - -

3 - 19 Werktage*

916,00 €
 
Cyclin A1, also known as CCNA1, is a 64kD protein that associates with the kinase Cdk2. This... mehr
Produktinformationen "Anti-Cyclin A1 (Cyclin-A1, CCNA1)"
Cyclin A1, also known as CCNA1, is a 64kD protein that associates with the kinase Cdk2. This complex phosphorylates multiple substrates involved in regulation of cell cycle progression, apoptosis, double strand DNA break repair, and mRNA splicing. Cyclin A1 activity promotes G2/M phase transition in spermatocyte meiosis and G1/S transition in somatic cells. Cyclin A1 is upregulated in myeloid leukemia, testicular germ cell tumors, and several carcinomas. It contains two cyclin box folds aa243-318 and 340-427. Over aa51-220, human Cyclin A1 shares approximately 75% aa identity with mouse and rat Cyclin A1. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml, Immunohistochemistry: 8-25ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: Anti-CCNA1, Anti-Cyclin-A1
Hersteller: United States Biological
Hersteller-Nr: C8452-71B

Eigenschaften

Anwendung: IHC, WB
Antikörper-Typ: Monoclonal
Klon: 12K76
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Recombinant corresponding to aa51-220 from human Cyclin A1 expressed in E.coli.
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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