Anti-ch-TOG

Anti-ch-TOG
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A301-970A-T 20 µl (2 blots) -

3 - 9 Werktage

125,00 €
A301-970A-M 100 µl (10 blots) -

3 - 9 Werktage

290,00 €
A301-970A 100 µl (20 µg) -

3 - 9 Werktage

430,00 €
 
Protein function: Binds to the plus end of microtubules and regulates microtubule dynamics and... mehr
Produktinformationen "Anti-ch-TOG"
Protein function: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Acts as processive microtubule polymerase. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubules from depolymerization by KIF2C and has an essential role in centrosomal microtubule assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch- TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubule attachments (PubMed:27156448). [The UniProt Consortium]
Schlagworte: Anti-CKAP5, Anti-Ch-TOG, Anti-KIAA0097, Anti-Cytoskeleton-associated protein 5, Anti-Colonic and hepatic tumor overexpressed gene protein
Hersteller: Bethyl Laboratories
Hersteller-Nr: A301-970A-T

Eigenschaften

Anwendung: WB, IP
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human (Erwartet: Mouse)
Immunogen: synthetic peptide. The epitope recognized by A301-970A-T maps to a region between residue 1425 and 1475 of human colonic and hepatic tumor over-expressed protein using the numbering given in entry NP_001008938.1 (GeneID 9793).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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