Anti-CES3

Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide. Identity-Mouse (%): 67%. Homologies: Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 46%, Pig - 76%, Cynomolgus monkey - 47%. IHC Verification: -. WB Verification: succeed. IP Verification: -. IF Verification: -. FC Verification: -. IP-MS Verification: -. Cross reactivity: Not tested. Sandwich ELISA Verification: -. Antigen ID: ABS-PQ-3244. Core Sequence: TGPEVAQPEV DTTLGRVRGR QVGVKGTDRL VNVFLGIPFA QPPLGPDRFS APHPAQPWEG VRDASTAPPM CLQDVESMNS SRFVLNGKQQ IFSVSEDCLV LNVYSPAEVP AGSGRPVMVW VHGGALITGA ATSYDGSALA AYGDVVVVTV QYRLGVLGFF STGDEHAPGN QGFLDVVAAL RWVQENIAPF GGDLNCVTVF GGSAGGSIIS GLVLSPVAAG LFHRAITQSG VITTPGIIDS HPWPLAQKIA NTLACSSSSP AEMVQCLQQK EGEELVLSKK LKNTIYPLTV DGTVFPKSPK ELLKEKPFHS VPFLMGVNNH EFSWLIPRGW GLLDTMEQMS REDMLAISTP VLTSLDVPPE MMPTVIDEYL GSNSDAQAKC QAFQEFMGDV FINVPTVSFS RYLRDSGSPV FFYEFQHRPS SFAKIKPAWV KADHGAEGAF VFGGPFLMDE SSRLAFPEAT EEEKQLSLTM MAQWTHFART GDPNSKALPP WPQFNQAEQY LEINPVPRAG QKFREAWMQF WSETLPSKIQ QWHQKQKNRK AQEDL. Recombinant Antibody: Protein Function: Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics [The Uniprot Consortium]